Structure-activity relationship of Aminoglycosides
SAR of Aminoglycosides antibiotics
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SAR of Aminoglycosides antibiotics
What is aminoglycosides? Aminoglycosides are classified as broad-spectrum antibiotics, their greatest usefulness lies in the treatment of serious systemic infections caused by aerobic gram-negative bacilli. They are the polycationic compounds that contain an aminocyclitol, usually 2-deoxystreptamine, or streptidine in streptomycin and related compounds, with cyclic amino-sugar attached by glycosidic linkages. Some of the amino glycoside … Read more
Physicochemical properties in relation to biological action
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