B pharmacy 7sem (NOVEL DRUG DELIVERY SYSTEM) Question bank

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NOVEL DRUG DELIVERY SYSTEM (B PHARMACY 7 SEMESTER) QUESTION BANK

UNIT-1 CONTROLL DRUG DELIVERY SYSTEM, POLYMERS

Long Essay (10 Marks)

  1. Explain the various requirements of drug candidate to be selected for formulation into controlled drug delivery system.
  2. Explain the principle involved in the design of controlled drug delivery systems.
  3. Describe the various physicochemical and pharmaceutical factors to be considered in selection of a drug candidate for controlled delivery formulations.
  4. Write the concept of controlled drug delivery systems. Explain the approaches for the Controlled release formulations based on diffusion.
  5. Write the concept of controlled drug delivery systems. Explain the approaches for the Controlled release formulations based on dissolution.
  6. Write the concept of controlled drug delivery systems. Explain the approaches for the Controlled release formulations based on ion exchange technique.

Short Answers (2 Marks)

  1. Define controlled drug delivery systems with examples.
  2. What are the advantages and disadvantages of controlled drug delivery systems?
  3. Define dissolution and diffusion.
  4. Name any two polymers used in the reservoir type of controlled drug delivery formulations.
  5. Name any two polymers used in the matrix type of controlled drug delivery formulations.
  6. Name any two ion exchange resins used in controlled drug delivery formulations.
  7. Define half life and protein binding.
  8. How the half life influence the design of controlled drug delivery systems.
  9. How the protein binding influence the design of controlled drug delivery systems.

UNIT-2 MICROENCAPSULATION

Long Essay (10 Marks)

  1. Define microencapsulation. Write the applications of microencapsulation. Explain phase separation-Coacervation technique.

Short Answers (2 Marks)

  1. Define core and coat materials with respect to microencapsulation.
  2. Define microencapsulation technique.
  3. Write the applications of microencapsulation.
  4. Name the techniques of microencapsulation

BUCCAL DRUG DELIVERY SYSTEMS

  1. What are buccal DDS? Explain the formulation of buccal drug delivery system. (10M)
  2. Write a note on the formulation of buccal drug delivery systems.(5M)
  3. Define buccal drug delivery systems.(2M)

IMPLANTS

  1. What is an implant? Explain the formulation of implants with a suitable example. 10M
  2. Explain concept, advantages and disadvantages of implants.5M
  3. What are implants?2M
  4. Give examples for implant drug delivery systems.2M

UNIT-3

TRANSDERMAL DRUG DELIVERY SYSTEMS (TDDS)

  1. What is transdermal DDS? Explain the different formulation approaches for transdermal DDS. (10M)
  2. Describe all the criteria to be considered for the selection of drugs to be formulated into a transdermal DDS with examples. (10)
  3. Explain any two formulation approaches for transdermal drug delivery systems.(5M)
  4. Describe the components of transdermal DDS.(5M)
  5. What is transdermal drug delivery?(2M)
  6. Name two marketed transdermal products.(2M)

GASTRORETENTIVE DRUG DELIVERY SYSTEM

NASOPULMONARY DRUG DELIVERY SYSTEM

  1. What are the advantages and disadvantages of nasal DDS? With the help of a neat labeled diagram explain the physiology of the nasal cavity with reference to nasal drug absorption. (10M)
  2. What is nasal drug delivery system? Write about its advantages and disadvantages.(5M)
  3. Explain the advantages of nasal drug delivery systems.(2M)
  4. What is nasal DDS?(2M)

UNIT-4

TARGETED DRUG DELIVERY SYSTEM

LIPOSOMES

  1. Define liposome. Explain the different methods of preparation of liposomes (10M.
  2. Explain concept, advantages and disadvantages of liposomes (5M).
  3. Define liposomes?(2M)

NIOSOMES

  1. What are vesicular DDS of niosomes? Explain the advantages, disadvantages and applications. 10M
  2. What are niosomes? Write its applications in target drug delivery system.5M
  3. Define niosomes.2M

NANOPARTICLES

  1. Define nanoparticle? Write the importance of nanoparticles in target drug delivery systems with suitable examples.10M
  2. Explain concept, advantages and disadvantages of nanoparticles.5M
  3. Define nanoparticles.2M
  4. How nanoparticles are used as target drug delivery systems.2M

MONOCLONAL ANTIBODIES

UNIT-5

OCCULAR DRUG DELIVERY SYSTEMS

10 MARKS

  1. Explain the characteristics of ocular drug delivery systems.
  2. What is ocular DDS? Explain its advantages, disadvantages and ideal requirements for ocular drug delivery systems.
  3. Define ocular drug delivery system. Explain different types of ocular DDS.

2 MARKS

  • Enumerate the different types of ocular dosage forms.2M
  • What are the ideal requirements for ocular drug delivery systems?2M
  • Define ocular drug delivery systems.2M

INTRAUTERINE DRUG DELIVERY SYSTEM

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