Table of Contents
Pharmaceutical inorganic chemistry Questions bank B pharmacy semester-1
This Pharmaceutical Inorganic chemistry Question bank was released by Rajiv Gandhi University of health and science Bangalore, this questions bank is arranged according to the syllabus, and unit-wise. It contains all the possible important questions of important topics.
UNIT-1 Pharmaceutical Inorganic chemistry Question bank
5marks
- Explain the principle and procedure for the limit test for sulphates.
- Write in detail the principle and reactions involved in the limit test for arsenic.
- Give the principle and procedure involved in the sulphate limit test.
- Write the principle involved in the limit test for arsenic.
- Write the principle of limit test for lead.
- Write the procedure and principle with reactions for limit test for lead.
- Write the principle and reaction involved in the heavy metals (IP) limit test.
- Give the principle, reactions involved in the limit test for iron and lead.
- Write in detail the principle, reactions and procedure for the limit test for iron.
- Explain briefly the implications of impurities in pharmaceutical substances.
- What do you mean by the term monograph? What are the contents of the monograph in Detail?
- Give a detailed account of the history of Pharmacopoeia.
- Write a note on Pharmacopoeia of India.
10 marks
- Describe the various sources of impurities present in pharmaceutical substances.
- Write briefly the different sources of impurities present in pharmaceutical substances..
- Explain the principle and procedure involved in the limit test of arsenic with a neat Labelled diagram of Gutziet’s apparatus.
- Give principle, procedure, reactions and role of reagents involved in the limit test for a) b) Lead-based on IP 1996 method.
- Explain the various sources of impurities in pharmaceuticals. Discuss the importance of
- Limit tests in quality control of pharmaceuticals.
- Write in brief the different sources of impurities present in pharmacopoeial substances.
- What are impurities? Explain different sources of impurities with examples.
- Write the procedure and principles for the limit tests for a) Sulphates b) Iron
- Describe the principle, apparatus and procedure for the limit test of arsenic.
- Define limit test? List out different limit tests you have studied. Discuss in detail the limit Test for sulphate and iron.
UNIT-2 Pharmaceutical Inorganic chemistry Question bank
Chapter: Acid-Base and Buffers
2marks
- Define the following terms i) Osmotic pressure ii) Isotonic solution.
- What is buffer capacity?
- Define buffers with examples.
- Define buffers. Give examples of two official buffers.
- What are buffer capacity and isotonicity?
- What is the importance of buffer in pharmacy?
- Define the term hypotonic and hypertonic.
- Define the term tonicity.
- What is osmotic pressure?
- Give any two examples of strong acid and weak acid.
- Give any two examples of a strong base and weak base.
- Write the limitations of Arrhenius theory.
5marks
- What are buffers derive from the Henderson-hasselbalch equation for buffers?
- What are buffered isotonic solutions? Give details.
- Explain the Lewis acid and Lewis base with examples.
- What is a buffer solution that explains the mechanism of buffer action?
- Write the importance of buffer solutions in pharmacy.
- Write a note on the isotonic buffer.
- Define acids and bases according to various concepts.
- Write a note on buffer solutions.
- Describe various methods used to adjust isotonicity.
10Marks
- Describe buffer capacity, stability of buffers, methods of adjusting isotonicity. Buffers and their role in pharmacy.
- Discuss various types of physiological buffers. Explain the mechanism of their Buffer action.
- Explain major buffers used in pharmaceutical preparations. What are the disadvantages of each? What factors must be taken into consideration in the Selection of a buffer?
- What are buffers? Explain the mechanism of buffer action with an example. Briefly discuss the role of buffers in pharmacy.
Chapter: Major Intra and extracellular electrolyte
2 Marks
- Give the composition of sodium chloride injection.
- What is the biological importance of sodium and chloride ions?
- What is milliequvalent per litre,
- Write the formula and uses of ORS.
- Classify extra and intracellular electrolytes with examples
- Give the method of preparation and uses of calcium gluconate injection.
5 MARKS
- Discuss the physiological acid-base balance in the body.
- Write a note on electrolytes used in replacement therapy.
- Explain the preparation, assay principle, storage conditions and medical uses of calcium Gluconate injection.
- Describe the physiological mechanism of acid-base balance in the body.
- What is electrolyte combination therapy? Explain a note on ORS.
- Explain the physiological role of sodium, calcium, chloride and bicarbonate ions.
- Give the principle and reaction involved in the assay of Calcium gluconate.
- Write a note on physiological acid-base balance.
- Write a note on a combination of electrolyte replacement therapy.
Chapter: Dental products
2 marks
- ✦ Write about zinc eugenol cement.
- What is an anticaries agent? Give example.
- What is dental caries? Name two anticaries agents.
- What is desensitizing agents? Give examples.
- What are Dentifricing agents? Give examples.
- What are dental products? Classify them with examples.
- Write the composition and application of zinc eugenol cement
5marks
- Discuss the role of fluorides in dental caries.
- What are dentifrices? Classify them with an example. Write a note on the role of fluoride as an Anticaries agent.
- Preparation and medicinal uses of calcium carbonate and sodium fluoride.
- Describe the method of preparation and uses of any two dental products.
UNIT-03 Pharmaceutical Inorganic chemistry Question bank
Chapter: Gastrointestinal agent
2 marks
- What Are antacids? Give examples.
- Define gastrointestinal protective agent. Give examples.
- Give the method of preparation of milk of magnesia.
- What is achlorhydria? Give its treatment.
- Define saline Cathartic give examples.
- Write the molecular formula and uses of milk of magnesia.
- Write the uses of aluminium hydroxide and magnesium hydroxide.
- Write the composition and uses of kaolin.
- Chemical composition and uses of magnesium trisilicate.
- Write two uses of NaHCO3.
- What are non-systemic antacids?
- Give the synonym of NaHCO3, MgSO4, magnesium hydroxide.
- Define antacids. Give examples
- Classify gastrointestinal agents for example.
- Write adverse effects of antacids.
- Write the pharmaceutical importance of Bentonite powder.
5 marks
- Give the method of preparation and uses of Aluminium hydroxide gel.
- Define and classify antacids with examples. Add a note on combination antacid Therapy.
- Define cathartics. Give the preparation and uses of any two cathartics.
- What are GIT agents? Classify them with examples. Write a note on acidifiers.
- What are antacids? Classify them with examples. State requirements for an ideal Antacid.
- Define and classify antacids? Discuss the preparation, assay principle and Medicinal uses of Baking soda.
- Write the principle for the assay of magnesium hydroxide.
- What are saline cathartics? What is their mechanism of action?
- Enlist different antacids. Write the preparation and uses of Magnesium Hydroxide.
- Write a note on antacid combination therapy.
- What are antacids? Classify them with examples. Give the method of Preparation, uses and assay of Sodium bicarbonate.
- What are gastrointestinal protectives and adsorbents. Write a short note on kaolin.
10marks
- What are Antacids? Classify them with examples. Give the ideal properties of Antacids. Write the preparation, assay and uses of sodium bicarbonate.
- Enlist in detail any drug with their molecular formula, synonym (if any) method of preparation and use belongs to magnesium, aluminium and sodium-containing antacid.
- Explain the principle, reaction and procedure involved in the assay of chlorinated lime and hydrogen peroxide.
Chapter: Antimicrobial agent
2marks
- What are antimicrobial agents? Give examples.
- Why sulphuric acid is added in the assay of Hydrogen peroxide.
- What is the use of glycerine in the boric acid assay?
- Define antimicrobial agent. List out the antimicrobial agents with molecular Formula.
- Preparation of boric acid?
- Give reasons: Dilute sulphuric acid used in the assay of hydrogen peroxide.
- Give the composition and method of preparation of Iodine tincture.
- Mention various preparations of iodine and their uses.
- What are antimicrobial agents? Give examples.
- Name two antimicrobials with their molecular formula.
- Write the molecular formula of boric acid and chlorinated lime.
- Write the synonym for bleaching powder and its uses.
- Write the molecular formula and uses of ZnO
- Write the molecular formula and uses of KMNO4.
- Write the molecular formula and uses of Boric acid,
5 marks
- Define antimicrobial agents. Write the principle involved in the preparation and assay of hydrogen peroxide.
- Describe the various mechanism of action of inorganic anti-microbial agents.
- What are anti-microbials? Give the method of preparation and principle in the assay of chlorinated lime.
- What are antimicrobials? Write a note on various iodine preparations.
- Write the preparation and uses of Chlorinated lime and boric acid.
- Explain the principle and reactions in the assay of Chlorinated lime.
UNIT-04 Pharmaceutical Inorganic chemistry Question bank
Chapter: Miscellaneous Agent
2 marks
- Define term antidotes. Give examples.
- haematinics? Give examples.
- Define emetics with examples.
- Give the chemical formula and medicinal use of sodium thiosulphate.
- Define expectorant and emetics Give examples.
- Give reasons a) Potassium iodide is used in the assay of Copper sulphate b) HCHO used in the assay of Ammonium chloride.
- What are expectorants? Give an example.
- Write pharmaceutical uses of activated charcoal and sodium thiosulphate.
- Define antidotes with examples.
- Write the molecular formula and medicinal uses of sodium thiosulphate.
- What are Haematinics? Give examples.
- What are antidotes? Give the method of preparation and importance of activated charcoal.
- Write the synonym for ferrous sulphate and copper sulphate.
5 marks
- Explain the method of preparation and assay of Ammonium chloride.
- Explain the principle and reactions involved in the assay of copper sulphate.
- What are Haematinics? Write the preparation and assay of ferrous sulphate.
- What are Haematinics? Explain the preparation and assay Of Green Vitriol.
- What are emetics? Write the method of preparation and assay Of Copper sulphate.
- What are expectorants? Give the method of assay of anyone expectorant.
- What are haematinics? Give the method of preparation, assay principle and Medicinal uses ferrous sulphate.
- What are expectorants? Give example and mechanism of action.
- Define and classify antidotes with examples. Write a note on activated charcoal.
- What is cyanide toxicity? What are the symptoms and treatment for cyanide Poisoning?
UNIT-05 Pharmaceutical Inorgaic chemistry Question bank
Chapter: Radiopharmaceuticals
2 marks
- What are radiopharmaceuticals?
- Give the importance of radioisotopes in pharmacy
- Define half-life.
- Write the uses of sodium iodide I131
- Define isotope.
- Write the storage condition of sodium iodide I131
- Give the precautionary measure required to handle radioactive substances.
5Marks
- Explain in detail any one method employed for the measurement of radioactivity.
- Describe the precautions for storage and handling of radioisotopes.
- Write a note on radiopharmaceutical sodium iodide I131
- What are radiopharmaceuticals? Discuss the importance of radioisotopes used in Medicine.
- Describe the properties of a, ß and y radiations.
- Explain the diagnostic and therapeutic applications of radioisotopes in Detail.
- Write the construction, working principle of the Geiger-muller counter With a neatly labelled diagram.
- Give a brief account of hazards associated with radiopharmaceuticals.
- Write the pharmaceutical application radioactive substances.