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Advanced instrumentation techniques question bank & Blueprint for B pharmacy 8 semester
Advanced instrumentation techniques question bank & Blueprint for B pharmacy 8 semesters is released by rguhs Bangalore, it contains all important questions, according to the syllabus. For Download the Questions bank click the download button given in below of this article.
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Long essay 10 marks instrumentation techniques question bank
- Write the principle involved in NMR spectrometer. Add a note on factors affecting on
Shielding and de -shielding in NMR Spectra. - Explain the principle and working of TGA. (Thermal gravimetric analysis)
- Discuss in detail the validation parameter for bio analytical methods as per ICH
guidelines. - Explain the fundamental principles and instrumental arrangements of NMR. Write a
detail note on Octant rule - Discuss the principle and working of DTA. (Differential Thermal Analysis)
- Discuss background and principles of Bio analytical method validation as per USFDA
regulations - Discuss in detail various ionization techniques employed in the Mass Spectroscopy.
- Explain the principle and working of TGA. (Thermal gravimetric analysis)
- Write the principle involved in crystallographic studies by X- ray diffraction. Give the
importance of Braggs law in X-ray diffraction spectroscopy. - Explain instrumentation of Mass Spectrometer and its applications.
- Discuss background and principles of Bio analytical method validation as per USFDA
regulations - Explain the production and detection of X-rays by Debye scherrer method
- Write a note on coupling and decoupling methods and its significance in NMR
Spectroscopy. - Explain the production and detection of X-rays by Debye Scherrer method.
- Discuss concept of TQM. Add a note on ICH-EG guidelines.
- Explain the principle involved in the Electron impact of MALDI ionization
techniques. Write its merits and demerits. Explain the Quadra pole mass analyzer. - Define and derive the Braggs law and explain rotating crystal technique.
Chemical ionization. - Discuss in detail the validation parameter for bio-analytical methods as per USFDA.
guidelines. - Write a note on Coupling and Decoupling methods in NMR Spectroscopy
- Explain validation of analytical method of LC as per ICH guidelines
- Write the principle of differential scanning calorimeter. What factors are responsible?
- Write a note on Coupling and Decoupling methods in NMR Spectroscopy.
- Explain validation of analytical method of LC as per ICH guidelines
- Define validation; explain the types of process validation
- Write a note on coupling and decoupling methods and its significance in NMR
Spectroscopy. - Discuss concept of TQM. Add a note on ICH-EG guidelines
- Discuss the instrumentation and application of TGA
- Explain the principle involved in the Chemical ionization. Write the merit and
demerits. Explain the working of Quadra pole and Ion trap mass analyzer. - Discuss the principle and working of DTA. (Differential Thermal Analysis)
- Write the principle involved in the X-ray crystallography. Explain the importance of
structural elucidation in X-ray diffraction spectroscopy
Short essay 5 marks instrumentation techniques question bank
- Explain chemical shift and factors influencing on Chemical shift.
- Discuss the instrumentation and application of DSC.
- Explain the methodology involved in the qualification of fluorimeter.
- Write a note on single crystal diffraction and powder diffraction.
- Classify different kinds of ELISA and explain each of them in details.
- Explain the methodology involved in the qualification of UV-VIS Spectrophotometer.
- Enlist different X-ray diffraction techniques and explain the any one detail.
- Describe the principle and procedure involved in the solid phase extraction.
- Explain the methodology involved in the qualification of GC.
- Write fragmentation process in Mass Spectroscopy.
- Describe the theory of Mass spectrometry
- Explain the methodology involved in the qualification of HPLC.
- Write the importance of Radio immune assay.
- Limitations and application of Radio Immuno Assay.
- Explain the various derivatization techniques in GC.
- Write the various applications of X-ray diffraction methods.
- Discuss the principle and application of DSC.
- Discuss in detail about the HPTLC technique
- Describe the rules for fragmentation of molecules in MS with suitable examples.
- Discuss the instrumentation and application of DSC.
- What is Chemical Shift? Explain with examples different factors influencing Chemical
Shift. - Discuss the identification powder diffraction pattern in X-ray diffraction spectroscopy.
- Classify different kinds of ELISA and explain each of them in details.
- Explain the methodology involved in the qualification of UV-VIS Spectrophotometer.
- Explain the principle and different methods of Radio Immuno Assay.
- Describe the principle and procedure involved in the solid phase extraction.
- What is theoretical plate, HETP, retention and asymmetry factor
- Discuss the principle and working of DTA.
- Describe the theory of Mass spectrometry
- Explain the methodology involved in the qualification of HPLC.
- Write the importance of Radio immune assay.
- Explain the concept of ELISA and its application as the diagnostic test for HIV.
- Explain validation parameter for electronic balance.
- Explain the terms of Chemical shift and Spin-Spin coupling, Coupling constant.
- Explain the chromatographic techniques and its applications
- Describe the principle and procedure involved in the solid phase extraction
- Explain Spin-Spin coupling and coupling constant.
- Discuss the instrumentation and application of DSC.
- Enlist the different X-ray Diffraction techniques and explain the application of X-ray
- diffraction.
- Explain the methodology involved in the qualification of UV-VIS Spectrophotometer.
- Describe the principle and procedure involved in the solid phase extraction.
- Discuss in detail cGmp guidelines according to CDER USFDA
- Discuss about design a qualification and describe the qualification GC.
- Explain the principle, advantages and requirements of Radio Immuno Assay.
- Define Chemical shift. Explain nuclear Over Hauser effect.
- Discuss the principle of NMR Spectroscopy.
- How are X-ray produced? What are modification of X-ray tube?
- Explain the principle and procedure involved in the liquid-liquid extraction.
- Explain the methodology involved in the qualification of GC.
- Describe the Radio Immunological assays and bioluminescence assay.
- Classify chromatographic methods and explain the instrumentation of HPLC
- What is theoretical plate, HETP, retention and asymmetry factor.
- Discuss the concept X-ray Crystallography.
- Briefly outline the instrumentation of Mass Spectrometer.
- State and derive the an equation for Braggs law.
- Explain the methodology involved in the qualification of HPLC.
- Explain the utilization of ELISA technology in the measurement of biological activities
- Write the various components, Limitations and application of Radio Immune Assay
- Explain validation parameter for electronic balance.
- Give a brief outline of principle of FT-NMR and CNMR
- Discuss in detail about the HPTLC technique.
- With a suitable diagram explain the construction and working of HPLC.
- Briefly outline the instrumentation of Mass Spectrometer.
- State and derive the an equation for Braggs law.
- Explain the methodology involved in the qualification of HPLC.
- Explain the utilization of ELISA technology in the measurement of biological activities
- Write the various components, Limitations and application of Radio Immune Assay
- Explain validation parameter for electronic balance.
- Enlist different ionizers used in MS and explain any one in detail.
- Discuss in detail about the HPTLC technique.
- Write the construction and working of HPLC.
- Explain the fragmentation pattern rules used in Mass spectroscopy.
- Explain the technique involved in thermal. Gravimetric analysis with suitable Examples
- Explain the different parts of Mass spectrometer with neat diagram.
- Explain the utilization of ELISA technology in the measurement of biological activities
- What are the factors to be considered during preparation of HPLC Analyses of drug
- products
- What is theoretical plate and explain any one detail.
- Discuss in detail the various detectors used in GC.
- Write note on bioluminescence assay, Enlist the application of ELISA.
- Explain the production and detection of X-rays by Debye Scherrer method.
- Explain the principle and instrumentation of NMR Spectroscopy.
- Write the principle of TGA. What factors are responsible for affecting TGA results
- Explain the terms of Chemical shift and Spin-Spin coupling, Coupling constant.
- Write the principle involved in the rotating crystal technique in X-ray diffraction
- spectroscopy.
- Explain the principle and different methods of Radio Immuno Assay.
- Explain the methodology involved in the qualification of HPLC.
- Describe the principle and procedure involved in the solid phase extraction.
- Explain the method involved in the qualification of
- Explain the various derivatization techniques in GC
Short answer 2 marks
- Enlist different ionizers used in MS.
- Define the Braggs law.
- Define and classify validation.
- Write the Limitations of Radio Immuno Assay.
- Differentiate between ELISA and RIA.
- Write applications of DTA.
- Important applications of IR.
- Write any one sampling technique of LC-MS.
- Name the ideal carrier gas used in Gas Chromatography
- What is HPTLC.?
- Solvent used in NMR Spectroscopy
- Applications of X Ray.
- Flame photometer
- ELISA.
- Define Radio Immuno Assay
- Spin-Spin coupling
- define Bragg’s law
- Important feature of qualification of UV-Visible.
- Classify different methods of Radio Immuno Assay
- HPTLC
- What is Shielding and De- shielding?
- What is single crystal diffraction.?
- Mention validation methods with examples
- Write the Limitations of Radio Immuno Assay.
- Application as the diagnostic test for HIV.
- Write its merits and demerits of HPLC.
- Write important applications of IR.
- Write sampling techniques of LC-MS.
- Qualification of UV Spectrophotometer.
- Detectors used in GC.
- Application of GC.
- Qualification of Fluorimeter.
- Define Singlet and Doublet.
- Applications of IR.
- Radio Immuno Assay
- Spin-Spin coupling
- What is plate theory and rate theory
- Important feature of qualification of UV-Visible.
- Define full validation and partial validation.
- Advantages of HPTLC.
- Classify different kinds of ELISA
- Define Singlet and Doublet.
- Define full validation and partial validation.
- Applications of IR.
- Radio Immune Assay.
- Qualification of IR Spectrophotometer.
- What is plate theory and rate theory
- Important feature of qualification of UV-Visible.
- Define Bragg’s law.
- Internal standard used in NMR.
- Factors influencing on Chemical Shift
- Write the concept of Miller indices
- Define Bragg’s law
- Name the detector used in Flame Photometer
- Qualification of IR Spectrophotometer
- Define ELISA and its uses
- Important feature of qualification of UV-Visible
- Application of GC
- Detection method methods in HPTLC
- Detectors used in HPLC
- Define quenching and give example
- Detector used in Flame Photometer.
- Define Singlet and Doublet.
- Enlist application of ELISA..
- Write the various components Radio Immune Assay
- Spin-Spin coupling
- What is plate theory and rate theory
- Enlist the ICH guidelines
- Define validation
- Advantages of HPTLC.
- Enumerate the application of HPTLC.
- Name the gases used in flame emission spectroscopy.
- Define Singlet and Doublet.
- Enlist the application of ELISA..
- Write the various components Radio Immune Assay
- Spin-Spin coupling
- What is plate theory and rate theory
- Define molecular ion and fragment ion
- Define validation
- Operational qualification
- Detectors used in GC.
- Define Coupling constant..
- What is Chemical Shift?
- Advantages of FT-IR Spectrophotometer
- Write the various components Radio Immune Assay
- Spin-Spin coupling
- What is rate theory?
- Installation qualification for UV
- Define validation
- Advantages of HPLC.
- What is Chemical shift? Write it significance
- Enlist the different X-ray Diffraction techniques.
- Define full validation & partial validation.
- Enumerate the different types of ELISA methods.
- Write importance of Radio Immuno Assay.
- Name the different derivatizations used in GC.
- Write the factors during preparation of HPLC Analyses drug products.
- Write sampling techniques of GC-MS.
- Define validation and explain different type of method validation
- 100.Detectors used in HPLC